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Request for proposalsConsulting · betaFederal buyer

High-throughput Unmasking of Biological Interactomes with Binding Landscape Emulators (HUBBLE)

DEPT OF DEFENSE, Virginia · DEFENSE ADVANCED RESEARCH PROJECTS AGENCY (DARPA) · DEF ADVANCED RESEARCH PROJECTS AGCY
Responses dueThu, Nov 510:00 AM ET · Virginia time27 days left
PostedWed, Oct 7No amendments since
Solicitation no.DARPA-PA-27-01SAM.gov
Set-asideNoneOpen to all firms

What the agency is buying

by RFPFinder from the notice and attachments; the solicitation governs

DARPA is soliciting proposals to develop an in-silico capability for mapping all protein-protein interactions, with applications to traumatic brain injury diagnostics and therapeutics. Awards will be made as Other Transactions (OT) with fixed payments for milestone completion.

Scope

  • Develop in-silico capability for mapping protein-protein interactions
  • Identify novel diagnostic and therapeutic targets for traumatic brain injury
Days to respond: 27

How to get the bid documents

  1. Download the 14 documents below (no portal account needed)
  2. Check the submission requirements in the compliance checklist
  3. Submit as the notice directs before 10:00 AM ET on Nov 5
Documents · 14 items, 14 filesDownload all (zip) · Pro
  • XLSX
    9c9b661857f74a1c8b802fd3f58f5855.xlsx28 KB
  • PPTX
    a7c598959ee14ef1909147849ccb6557.pptx89 KB
  • DOCX
    b2c96781e51e4d5b98757392621f670a.docx30 KB
  • DOCX
    c716629e1cff4652ad8a1a9b775ff4cc.docx45 KB
  • DOCX
    d81db027570343c39fe8af9bd8932221.docx161 KB
  • XLSX
    de505af45e014b61b770f3e9e2eedc16.xlsx553 KB
  • PDF
    e416a682594c4abb8ce139edb3f32eb2.pdf960 KB · 23 pages
  • PDF
    DARPA-PA-27-01.pdf960 KB · 23 pages
  • DOCX
    Attachment_B_DARPA-PA-26-10__Model_OT_for_Research_HUBBLE_20261008.docx161 KB
  • PPTX
    Attachment_F_Risk_Matrix_HUBBLE.pptx89 KB
  • DOCX
    Attachment_E_Task_Description_Document_HUBBLE.docx30 KB
  • XLSX
    Attachment_D_Schedule_Milestone_and_Payments.xlsx28 KB
  • XLSX
    Attachment_C_Cost_Proposal_Spreadsheet_HUBBLE.xlsx553 KB
  • DOCX
    Attachment_A_Abstract_Template_and_Instructions__Phase_1_.docx45 KB
Open the original listing on SAM.gov

Details

Place of performance
ARLINGTON, Virginia
Buyer type
Federal
Notice type
Solicitation
Solicitation no.
DARPA-PA-27-01
Category
Consulting · beta
NAICS
NAICS 541714 (Research and Development in Biotechnology (except Nanobiotechnology)): 13 open RFPs
PSC
PSC AC12
Period of performance
12 months base from attachment p.1
Contract type
Other Transaction (OT) from attachment p.1
Local presence
Not required
Amendments
None since Oct 7
Contact
Dr. Abhishek Singharoy, DARPA/BTO
Office
DEFENSE ADVANCED RESEARCH PROJECTS AGENCY (DARPA) · DEF ADVANCED RESEARCH PROJECTS AGCY
Email
HUBBLE@darpa.mil

Not stated in the notice: estimated value. Check the bid documents.

Contact details from the source notice. Contact the buyer only about this solicitation.

Key dates

Wed, Oct 7Posted
Not statedQuestions due
Thu, Nov 5 · 10:00 AM ETResponses due · 27 days left

Change log

verified Fri, Oct 9 · 12:30 AM ET

No amendments since posting on Wed, Oct 7; verified Fri, Oct 9 · 12:30 AM ET.

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Notice as published

High-throughput Unmasking of Biological Interactomes with Binding Landscape Emulators (HUBBLE)

The Defense Advanced Research Projects Agency (DARPA) is soliciting proposals to develop an in-silico capability for mapping all protein-protein interactions. Utility of this capability will be demonstrated in identifying novel diagnostic and therapeutic targets within the interaction space underlying including traumatic brain injury.

What this office paid before

USAspending.gov, last 36 months

25 awards matched · tier 1: this contracting office (HR0011) + PSC AC12. Most recent:

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Awards updated Fri, Oct 9, 2026 · 8:56 AM ET.

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same PSC AC12

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