What the agency is buying
by RFPFinder from the notice and attachments; the solicitation governsDARPA is seeking proposals for the Protein ENGineering (PENG) program to develop a multifunctional platform for precise, programmable editing of endogenous proteins. This is an Other Transaction for Prototypes agreement, with fixed payments made upon completion of milestones.
Scope
- Develop a multifunctional, target-agnostic platform for precise, programmable editing of endogenous proteins.
- Integrate novel splicing, ligation, and co-translational techniques to modify and rewrite endogenous proteins.
1 signal behind this label (incumbent, repeat winner, short window, brand-name or sole-source language, prior sources sought). Pro shows them with sources.
From USAspending awards and the notice text, recomputed nightly (Oct 7). A signal, not a verdict.
How to get the bid documents
- Download the 13 documents below (no portal account needed)
- Check the submission requirements in the compliance checklist
- Submit by unknown before 12:00 PM ET on Oct 19
Details
- Place of performance
- ARLINGTON, Virginia
- Buyer type
- Federal
- Notice type
- Solicitation
- Solicitation no.
- DARPA-PS-26-129
- Contract type
- Other Transaction for Prototypes from attachment p.1
- Local presence
- Not required
- Amendments
- 1, last Aug 21
- Contact
- BAA Coordinator
- Office
- DEFENSE ADVANCED RESEARCH PROJECTS AGENCY (DARPA) · DEF ADVANCED RESEARCH PROJECTS AGCY
- PENG@darpa.mil
Not stated in the notice: estimated value, period of performance. Check the bid documents.
Contact details from the source notice. Contact the buyer only about this solicitation.
Key dates
- Amendment 1
- Fri, Aug 21
Change log
verified Thu, Oct 8 · 12:30 AM ET- Posted · SolicitationFri, Aug 7 · 7:37 AM ET
- Amendment · New version of the notice posted at the sourceFri, Aug 21 · 9:27 AM ET
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Notice as published
Protein ENGineering (PENG)
The Defense Advanced Research Projects Agency (DARPA) is soliciting innovative proposals for the development of a multifunctional, target-agnostic platform for precise, programmable editing of endogenous proteins. The goal of the Protein ENGineering (PENG) program is to transition proteome engineering from a collection of isolated, bespoke tools into a universal, software-defined discipline. The PENG program will establish a comprehensive, integrated platform composed of modular targeting, generalizable effector chemistries, and multiplexed control systems.
Rather than developing isolated, target-specific tools, performers will integrate novel splicing, ligation, and co-translational techniques to directly recognize, modify, and rewrite endogenous proteins within complex biological architectures. Performers may explore multiple technical paths, progressively advancing their approaches from foundational validation to robust demonstrations of efficacy. Ultimately, this integrated platform will be validated in high-fidelity cellular models (e.g., organoids), to provide an integrated proof-of-concept at the tissue level.
What this office paid before
USAspending.gov, last 36 months25 awards matched · tier 1: this contracting office (HR0011) + PSC AC12. Most recent:
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This contracting office
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same PSC AC12Listing collected from SAM.gov. Always confirm requirements in the original solicitation before you bid.