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Special noticeFederal buyer

Non-Optical Methods for High Speed Protein Control

DEPT OF DEFENSE, Virginia · DEFENSE ADVANCED RESEARCH PROJECTS AGENCY (DARPA) · DEF ADVANCED RESEARCH PROJECTS AGCY
Verified 23 h agoAmended Jun 8
Responses dueTue, Dec 811:00 AM ET · Virginia time61 days left
PostedMon, Jun 82 amendments, last Jul 21
Solicitation no.DARPA-SN-26-89SAM.gov
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What the agency is buying

by RFPFinder from the notice and attachments; the solicitation governs

DARPA BTO seeks innovative solutions for non-optogenetic protein domains for real-time cellular control. Offers will be evaluated for their potential to address the need for a new class of rapidly switchable protein domains.

Scope

  • Non-optical methods for high speed protein control
  • Rapidly switchable, non-optogenetic protein domains
Days to respond: 61

How to get the bid documents

  1. Download the 2 documents below (no portal account needed)
  2. Check the submission requirements in the compliance checklist
  3. Submit as the notice directs before 11:00 AM ET on Dec 8
Documents · 2 items, 2 filesDownload all (zip) · Pro
  • PDF
    DARPA-SN-26-89-Amendment-01.pdf37 KB · 1 page
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  • PDF
    DARPA-SN-26-89.pdf143 KB · 3 pages
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Details

Place of performance
ARLINGTON, Virginia
Buyer type
Federal
Notice type
Special Notice
Solicitation no.
DARPA-SN-26-89
NAICS
NAICS 541714 (Research and Development in Biotechnology (except Nanobiotechnology)): 13 open RFPs
PSC
PSC AC12: 24 open RFPs
Local presence
Not required
Amendments
2, last Jul 21
Contact
Dr. Matthew Pava, DARPA/BTO
Office
DEFENSE ADVANCED RESEARCH PROJECTS AGENCY (DARPA) · DEF ADVANCED RESEARCH PROJECTS AGCY
Email
ERIS@darpa.mil

Not stated in the notice: estimated value, contract type, period of performance. Check the bid documents.

Contact details from the source notice. Contact the buyer only about this solicitation.

Key dates

Mon, Jun 8Posted
Not statedQuestions due
Dec 31 Tue, Dec 8 · 11:00 AM ETResponses due · 61 days left
Amendment 1
Tue, Jul 21
Amendment 2
Tue, Jul 21

Change log

verified Thu, Oct 8 · 12:30 AM ET
  1. Posted · Special NoticeMon, Jun 8 · 7:07 AM ET
  2. Amendment · New version of the notice posted at the sourceTue, Jul 21 · 5:07 AM ET
  3. Deadline moved · Tue, Dec 8, 2026 · 11:00 AM ET → Thu, Dec 31, 2026 · 6:59 PM ETTue, Jul 21 · 5:07 AM ET
  4. Amendment · New version of the notice posted at the sourceTue, Jul 21 · 9:55 AM ET
  5. Deadline moved · Thu, Dec 31, 2026 · 6:59 PM ET → Thu, Dec 31, 2026 · 11:59 PM ETTue, Jul 21 · 9:55 AM ET
  6. Updated · The government procurement notice has been updated to include additional information about the project's goals and objectives.Wed, Oct 7 · 12:33 AM ET
  7. Deadline moved · Thu, Dec 31, 2026 · 11:59 PM ET → Tue, Dec 8, 2026 · 11:00 AM ETWed, Oct 7 · 12:34 AM ET
  8. Deadline moved · Tue, Dec 8, 2026 · 11:00 AM ET → Thu, Dec 31, 2026 · 11:59 PM ETThu, Oct 8 · 12:32 AM ET
  9. Deadline moved · Thu, Dec 31, 2026 · 11:59 PM ET → Tue, Dec 8, 2026 · 11:00 AM ETThu, Oct 8 · 12:32 AM ET

Change log starts Oct 5, 2026 (tracking began); earlier amendments at SAM.gov are being pulled in.

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Notice as published

Non-Optical Methods for High Speed Protein Control

DARPA BTO will be actively shopping the ERIS Marketplace for innovative, post-competitive, awardable solutions that address the need for a new class of rapidly switchable, non-optogenetic protein domains for real-time cellular control. This effort seeks to develop a robust and versatile molecular tool for massless information transfer across a cell membrane, intended to supplement existing synthetic biology platforms.

What this office paid before

USAspending.gov, last 36 months

25 awards matched · tier 1: this contracting office (HR0011) + PSC AC12. Most recent:

  • Jun 8, 2026ENGINEERING BIOLOGY RESEARCH CONSORTIUMRISK ANALYSIS AND POLICY RECOMMENDATIONS FOR TECHNICAL OUTPUTS OF THE DARPA GENERATIVE OPTOGENETICS PROGRAMHR001126CE079 · DEFINITIVE CONTRACT · Defense Advanced Research Projects Agency · ends Jun 7, 2027$188K
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Awards updated Thu, Oct 8, 2026 · 11:34 PM ET.

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